Article Text
Statistics from Altmetric.com
Q In patients with dyspepsia, is 1 day quadruple therapy non-inferior to 7 day triple therapy for eradication of Helicobacter pylori infection?
Clinical impact ratings GP/FP/Primary care ★★★★★★☆ IM/Ambulatory care ★★★★★★☆ Gastroenterology ★★★★★☆☆ Infectious disease ★★★☆☆☆☆
METHODS
Design:
randomised controlled trial.
Allocation:
{concealed*}†.
Blinding:
unblinded.*
Follow up period:
5 weeks.
Setting:
ambulatory internal medicine clinics of 2 university affiliated hospitals in Canton, Ohio, USA.
Patients:
160 patients aged ⩾18 years (mean age 50 y, 57% women) who had dyspepsia and H pylori infection, a Glasgow Dyspepsia Severity Score (GDSS) ⩾3 (score range 0–20), and a positive carbon 14 urea breath test result. Exclusion criteria included previous treatment of H pylori infection, pregnancy, personal or family history of gastrointestinal malignancy, antibiotic therapy in the previous 6 weeks, previous gastric surgery, and hepatic insufficiency.
Interventions:
1 day regimen of 2 …
Linked Articles
- Glossary