Penicillin V (PCV) for 7 days (PCV7) or 3 days (PCV3) v placebo in children 4–15 years of age with a sore throat at 7 days*
| Outcomes | Culture results | n | Comparison | Means | Difference between groups (95% CI) |
|---|---|---|---|---|---|
| *CI defined in glossary. | |||||
| †Significant outcome favours placebo. | |||||
| Duration of sore throat symptoms (d) | All children | 156 | PCV7 v placebo | 3.8 v 3.8 | 0.0 (−0.9 to 0.9) |
| PCV3 v placebo | 4.6 v 3.8 | 0.8 (−0.1 to 1.7) | |||
| Positive for group A streptococci | 96 | PCV7 v placebo | 3.0 v 3.5 | −0.5 (–1.5 to 0.6) | |
| PCV3 v placebo | 4.8 v 3.5 | 1.3 (0.2 to 2.4)† | |||
| Other or negative for group A streptococci | 60 | PCV7 v placebo | 4.9 v 4.7 | 0.2 (−2.0 to 1.6) | |
| PCV3 v placebo | 4.4 v 4.7 | –0.3 (–1.4 to 1.9) | |||
