Evid Based Med 9:156 doi:10.1136/ebm.9.5.156
  • Clinical prediction guide

The BODE index predicted death in chronic obstructive pulmonary disease

 Q In patients with chronic obstructive pulmonary disease (COPD), how well does an index comprising the risk factors that reflect the respiratory, perceptive, and systemic aspects of the disease predict outcome?

Clinical impact ratings GP/FP/Primary care ★★★★★★☆ IM/Ambulatory care ★★★★★★☆ Internal medicine ★★★★★★☆ Respirology ★★★★★★☆



2 cohort studies, 1 for development and 1 for validation.


clinics in the US, Venezuela, and Spain.


832 patients (mean age 66 y) who had COPD with a wide range of severity, were in clinically stable condition, and were receiving appropriate therapy. Exclusion criteria: probability of death within 3 years from a cause other than COPD, asthma, inability to take the lung function and 6 minute walk tests, myocardial infarction within the previous 4 months, unstable angina, or congestive heart failure. 207 patients were recruited from 1995 to 1997 and formed the development cohort; 625 patients were recruited from 1997 to 2003 …