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The reduction in major cardiovascular and cerebrovascular events with statins extends beyond their lipid-lowering effects.1 Other pleiotropic benefits have also been ascribed to them,2 including reduction in blood pressure.3 Even small (∼5 mm Hg) decrements in blood pressure can have significant impact on morbidity and mortality. Current literature shows conflicting results regarding the efficacy of statins in controlling hypertension.3 4
The original PHYLLIS trial5 was a double-blinded, multicentre, randomised controlled trial that included 508 men and postmenopausal women with untreated hypertension, hypercholesterolemia and asymptomatic carotid artery atherosclerosis. Subjects were divided …
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