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In its most severe form, alcoholic hepatitis is associated with jaundice, coagulopathy, leucocytosis and rapid deterioration to death.1 When used in conjunction with abstinence from alcohol, corticosteroids improve 6-month survival for such severely affected patients.2 Treatment failures are identified after 7 days of therapy, using a simple mathematical instrument (http://www.lillemodel.com).3 Patients with alcoholic hepatitis who are unresponsive to medical management have a dire 6-month mortality.
Widely-used selection rules exclude patients with alcoholic hepatitis from liver transplantation (LT) unless they demonstrate 6 months of abstinence from alcohol.4 ,5 The study by Mathurin et al used …
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