Evid Based Med doi:10.1136/eb-2012-100962
  • Aetiology
  • Cohort study

Increased incidence of cardiovascular disease: are low-carbohydrate–high-protein diets truly to blame?

  1. Elizabeth Rolland-Harris2
  1. 1Centre for Obesity Research and Epidemiology, Robert Gordon University, Aberdeen, UK
  2. 2Department of National Defence, Directorate of Force Health Protection, Ottawa, Ontario, Canada
  1. Correspondence to: Dr Catherine Rolland
    Centre for Obesity Research and Epidemiology, Robert Gordon University, St. Andrew Street, Aberdeen AB25 1HG, UK c.rolland{at}

Commentary on:


Low-carbohydrate—high-protein diets have become popular in developed countries as an aid to weight loss. However, uncertainties about their effectiveness in weight loss and concerns about long-term adverse impacts on cardiovascular health remain. Several systematic reviews1 ,2 have concluded that, with the increasing prevalence of obesity, there is a need for long-term evidence/studies of low-carbohydrate diets. The authors investigate the long-term consequences of low-carbohydrate diets (LCHD) on cardiovascular health in a female Swedish population.


Women aged 30–49 recruited from the Swedish Women's Lifestyle and Health cohort were followed for a mean of 15.7 years. A self-administered questionnaire was used to assess lifestyle, physical activity …

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