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Evid Based Med doi:10.1136/eb-2012-101010
  • Therapeutics
  • Systematic review

HIV consensus guideline recommends antiretroviral treatment regardless of CD4 count, new regimens and possible regimen change for chronic low level viraemia

  1. R Chris Rathbun
  1. Department of Pharmacy: Clinical/Administrative Sciences, OUHSC College of Pharmacy, Clinical/Administrative Sciences, Oklahoma City, Oklahoma, USA
  1. Correspondence to: R Chris Rathbun
    Department of Pharmacy: Clinical/Administrative Sciences, OUHSC College of Pharmacy, Clinical/Administrative Sciences, 1110 N. Stonewall, Rm 206, Oklahoma City, OK 73117, USA; Chris-Rathbun{at}ouhsc.edu

Commentary on:

Context

Recommendations for indications and timing of antiretroviral therapy have continued to evolve since the introduction of highly active antiretroviral therapy. Updated guidelines from the International Antiviral Society (IAS)—USA Panel have recently been issued to inform clinicians in resource-rich settings of best practices based on treatment advances and increased understanding of HIV pathophysiology.

Methods

Consensus antiretroviral therapy guidelines were last issued from the IAS-USA Panel in July 2010. The current update is based on a systematic search of literature indexed in PubMED and EMBASE between July 2010 and May 2012, scientific conference abstracts, data/safety monitoring board and regulatory agency reports …

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