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Evid Based Med doi:10.1136/eb-2012-101171
  • Prognosis
  • Cohort study

Women whose cervical intraepithelial neoplasia has been treated or resolved remain at continued high risk for cervical cancer

  1. Mark H Einstein
  1. Department of Obstetrics & Gynecology and Women's Health, Albert Einstein College of Medicine and Montefiore Medical Center, Bronx, New York, USA
  1. Correspondence to: Mark H Einstein, MD, MS
    Department of Obstetrics & Gynecology and Women's Health, Albert Einstein College of Medicine and Montefiore Medical Center, 1695 Eastchester Rd, Suite 601, Bronx, NY10461, USA; mark.einstein{at}einstein.yu.edu

Commentary on:

Context

There is growing evidence that women who develop clinically significant cervical intraepithelial neoplasia (CIN) have continued risk of cervical cancer after adequate treatment or after natural regression. Also, there is no harmonisation of management guidelines across different screening programmes for the post-treatment follow-up of CIN, despite similar risks in populations globally.

Methods

This was a population-based cohort study based in the Netherlands. The data were prospectively collected in the Netherlands registry, with nearly 100% coverage of laboratory data and the ability to avoid duplication and false identity matches. Also, to provide further …