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Urinary tract infections (UTIs) represent a considerable healthcare burden, with important consequences in terms of morbidity and cost. Preventive measures are limited, not always dramatically effective1 and associated with a concerning increase in the resistance profile of common pathogens to different antibiotics. Thus, there is considerable interest in alternative prophylactic interventions. Among these, cranberry products (CP) are often recommended and utilised. The study by Jepson and colleagues updates a previous analysis on the use of CP for this purpose.
The authors conducted a systematic review and meta-analysis (SR/MA) of pertinent literature identified by a comprehensive search strategy with an in-depth assessment of randomised and quasi-randomised trials of CP (vs placebo and non-placebo controls) in preventing UTIs. Two investigators independently evaluated and extracted information on methods, participants, interventions …
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