You are here

Article Text

Article menu
Download PDFPDF
Aetiology
Cohort study
Maternal folic acid supplements associated with reduced autism risk in the child
  1. Rebecca J Schmidt
  1. Public Health Sciences, University of California Davis, Davis, California, USA
  1. Correspondence to Dr Rebecca J Schmidt
    Public Health Sciences, University of California Davis, One Shields Ave, Davis, CA 95616, USA; rjschmidt{at}ucdavis.edu

https://doi.org/10.1136/eb-2013-101311

Statistics from Altmetric.com

    Request Permissions

    If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.

    Commentary on: Surén P, Roth C, Bresnahan M, et al. Association between maternal use of folic acid supplements and risk of autism spectrum disorders in children. JAMA 2013;309:570–7.OpenUrlCrossRefPubMedWeb of Science

    Context

    Autism spectrum disorder (ASD) prevalence is increasing. Maternal periconceptional folic acid intake was associated with reduced ASD risk in a large, population-based case–control study.1 Surén and colleagues examined whether maternal folic acid supplements were associated with reduced risk for ASD.

    Methods

    The Norwegian Mother and Child Cohort Study (MoBa) included 85 176 children at least 3 years old born between 1999 and 2009. Questionnaire information on maternal supplement use was obtained around 18-week gestation.

    Findings

    The 270 MoBa children diagnosed with ASD included 114 with autistic disorder, 56 with Asperger syndrome and 100 with pervasive developmental disorder, not otherwise specified (PDD-NOS). Of the 61 042 children whose mothers took folic acid from 6 weeks before to …

    View Full Text

    Footnotes

    • Competing interests None.