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Systematic review and meta-analysis
Prophylactic antibiotics for caesarean section administered preoperatively rather than post cord clamping significantly reduces the rate of endometritis
  1. R F Lamont1,2,
  2. J S Joergensen2
  1. 1Division of Surgery, University College London,Northwick Park Institute of Medical Research Campus, Harrow, Middx, London, HAI 3UJ, UK
  2. 2Department of Obstetrics and Gynaecology, University of Southern Denmark, Odense University Hospital, Sdr Boulevard 29, 5000 Odense C, Denmark
  1. Correspondence to: Professor Ronald F Lamont University of Southern Denmark, Sdr Boulevard 29, Odense, 5000 Odense C, Denmark;rflamont{at}aol.com

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Antibiotic prophylaxis for women undergoing caesarean section (CS) has been proven to be beneficial in decreasing post-CS infectious morbidity in women at high-risk (in labour after membrane rupture), as well as low-risk (non-labouring with intact membranes).1 Evidence-based guidelines recommend the use of prophylactic antibiotics before surgical incision. An exception is made for CS, where narrow-range antibiotics are administered after umbilical cord clamping because of putative neonatal benefit. The use of preincision, broad-spectrum antibiotics may result in a lower rate of maternal morbidity with no disadvantage to the neonate.2 This systematic review and meta-analysis examines the maternal and neonatal …

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