Article Text

other Versions

PDF
Systematic review and meta-analysis
Central venous pressure cannot predict fluid-responsiveness
  1. Maurizio Cecconi,
  2. Hollman D Aya
  1. Department of Intensive Care Medicine, St George's Hospital, London, UK
  1. Correspondence to: Dr Maurizio Cecconi, Critical Care, St George's Hospital, Blackshaw Road, London SW170QT, UK; m.cecconi{at}nhs.net

Statistics from Altmetric.com

Commentary on: OpenUrlCrossRefPubMedWeb of Science

Context

Central venous pressure (CVP) has been extensively studied in relation to preload and preload responsiveness. In 2008 Marik et al1 showed the inability of CVP and Δ-CVP to evaluate blood volume status and predict fluid-responsiveness in a systematic review and meta-analysis of 24 studies. In spite of that level of evidence, surviving sepsis campaign guidelines still recommend targeting CVP in order to guide fluid therapy in severe sepsis and septic shock. Interestingly, in Rivers’ study,2 one of the studies referenced to use CVP, the same CVP target values were used in the control as well as …

View Full Text

Request permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.