Article Text

other Versions

Cohort study
Long-term follow-up after removal of colorectal adenomas provides evidence for risk stratification of patients at colonoscopic polypectomy
  1. Sidney J Winawer
  1. Memorial Sloan Kettering Cancer Center, New York, New York, USA
  1. Correspondence to : Dr Sidney J Winawer, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA; winawers{at}

Statistics from

Commentary on: OpenUrlCrossRefPubMedWeb of Science


The association of colorectal cancer (CRC) with pre-existing adenomatous polyps was challenged for decades until the National Polyp Study (NPS) demonstrated that colonoscopic polypectomy prevented deaths from CRC.1 In a follow-up of the Minnesota Colon Cancer Control study (46 551 participants), those randomly assigned to annual screening with a sensitive faecal occult blood test, sustained a 32% CRC mortality reduction over 30 years which was consistent with the effect of polypectomy.2 In the Nurses’ Health Study and the Health Professional Follow-up Study (88 902 participants followed over 22 years), lower endoscopy was associated with a 43% CRC mortality reduction compared to no endoscopy.3 …

View Full Text

Request permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.