Article Text
Therapeutics/Prevention
Randomised controlled trial
Up to 4000 mg of paracetamol a day is ineffective for acute low back pain
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Context
Back pain affected 9% in a global prevalence study1 and acute low back pain had an incidence of 38/1000 person-years in a large US armed forces survey.2 It is a common reason for seeing a general practitioner. Paracetamol taken regularly is advised as the first drug treatment option by the National Institute for Health and Care Excellence (NICE).
Methods
This large (N=1650) randomised, double-blind, double-dummy clinical trial tested paracetamol in acute low back pain.3 Regular paracetamol (3 times per day, 3990 mg) and as-needed …
Footnotes
Competing interests None.
Provenance and peer review Commissioned; internally peer reviewed.