Article Text
Aetiology/Harm
Case–control
Cotrimoxazole is associated with sudden death in older patients receiving inhibitors of renin–angiotensin system
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Context
ACE inhibitors (ACEIs) and angiotensin receptor blockers (ARBs) are commonly prescribed to older patients with hypertension, heart failure (HF) and chronic kidney disease (CKD) and may increase serum potassium (K) levels. Cotrimoxazole, a common antibiotic used to treat urinary tract infections, may also raise serum K levels, especially in patients also taking other drugs that raise serum K …
Footnotes
Competing interests None.
Provenance and peer review Commissioned; internally peer reviewed.