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Early clinical trials comparing coronary artery bypass graft (CABG) surgery to medical treatments in the 1970s and 1980s indicate an improved survival for surgery patients with left ventricular (LV) dysfunction. However, patients with severe LV dysfunction were not represented in these trials.1 Surgical Treatment for Ischaemic Heart Failure (STICH) was a trial aimed at comparing CABG surgery to the optimal medical therapy in ischaemic cardiomyopathy patients with an ejection fraction (EF) <0.35. A major secondary end point of the trial was health-related quality of life (QOL). These are the outcomes presented in this paper.
Patients (n=1212) with EF of 0.35 or less and coronary artery disease …
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