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Randomised controlled trial
In patients with persistent atrial fibrillation complex ablation techniques were no better than pulmonary vein isolation alone in preventing recurrent atrial fibrillation
  1. Martin Manninger,
  2. Daniel Scherr
  1. Division of Cardiology, Medical University of Graz, Graz, Austria
  1. Correspondence to: Dr. Daniel Scherr, Associate Professor of Medicine, Division of Cardiology, Medical University of Graz, Auenbruggerplatz 15, Graz 8036, Austria; daniel.scherr{at}medunigraz.at

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Context

Pulmonary vein isolation (PVI) is a well-established treatment for patients with paroxysmal atrial fibrillation (AF).1 ,2 Ablation of persistent AF (beyond 7 days) or longstanding persistent AF (>12 months) is less likely to result in permanent sinus rhythm.1 ,2 For this reason, additional ablation methods subsumed as ‘substrate modification’ are often combined with PVI. These methods include ablation of complex fractionated atrial electrograms (CFAEs) and/or creation of linear lesions within the left atrium.

Methods

The study reported on a randomised trial …

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