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Superiority trials: raising the bar of null hypothesis statistical testing
  1. Nusrat Shafiq,
  2. Samir Malhotra
  1. Department of Pharmacology, Postgraduate Institute of Medical Education & Research, Chandigarh, India
  1. Correspondence to : Dr Samir Malhotra
    , Department of Pharmacology, Postgraduate Institute of Medical Education & Research, Chandigarh 160012, India; smal.pgi{at}gmail.com

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We propose a ‘superiority margin’, akin to the non-inferiority margin used in non-inferiority trials. This would overcome several drawbacks of null hypothesis statistical testing and can be applicable to other types of analyses as well.

  • CLINICAL PHARMACOLOGY

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We propose a ‘superiority margin’, akin to the non-inferiority margin used in non-inferiority trials. This would overcome several drawbacks of null hypothesis statistical testing and can be applicable to other types of analyses as well.

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