Statistics from Altmetric.com
Ovarian cancer is the most fatal gynaecological malignancy. Most cancers are detected at advanced stages when therapeutic options are limited. Epithelial ovarian cancers are heterogeneous with respect to cell of origin, molecular pathways, morphological appearance, risk factor associations and survival.1 ,2 High-grade serous carcinomas are most common and have the worst prognosis. Currently, proposed ovarian cancer screening strategies include transvaginal ultrasound and CA-125 blood testing. In a previous randomised controlled trial evaluating these strategies, no mortality benefit was observed.3
In the UK Collaborative Trial of Ovarian Cancer Screening (UKCTOCS), around 200 000 women aged 50–74 were enrolled and randomly assigned to …
If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.