Article Text

PDF
Randomised controlled trial
Caffeine does not increase the arrhythmic burden in patients with heart failure and left ventricular systolic dysfunction
  1. Daniel Caldeira
  1. Laboratório de Farmacologia Clínica e Terapêutica, Faculdade de Medicina, Universidade de Lisboa, Lisboa, Portugal
  1. Correspondence to Professor Daniel Caldeira, Laboratório de Farmacologia Clínica e Terapêutica, Faculdade de Medicina, Universidade de Lisboa. Av. Prof. Egas Moniz, Lisboa, 1649-028, Portugal; dgcaldeira{at}hotmail.com

Statistics from Altmetric.com

Commentary on: Zuchinali P, Souza GC, Pimentel M, et al, . Short-term effects of high-dose caffeine on cardiac arrhythmias in patients with heart failure: a randomized clinical trial. JAMA Intern Med 2016;176:1752–9.

Context

Caffeine is a major component of some of the most widely consumed beverages, such as coffee. The role of caffeine in arrhythmias has always been controversial and the impact of caffeine on patients at high risk of arrhythmias it is not established.

Methods

This was a single-centre double-blinded randomised controlled trial (RCT) comparing the effect of caffeinated coffee (capsules with 100 mg of caffeine given hourly with decaffeinated coffee until 500 mg) and decaffeinated coffee (placebo lactose capsules) in patients with chronic heart failure (HF), New York Heart Association (NYHA) classes between I and III and left ventricular (LV) …

View Full Text

Request permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.