Intensive lifestyle intervention (ILS) or metformin plus standard lifestyle v placebo plus standard lifestyle for prevention of metabolic syndrome*
| Outcome at mean 3.2 years | Comparisons | Cumulative incidence | RHR (95% CI) | NNT (CI)† |
|---|---|---|---|---|
| *RHR = relative hazard reduction. Other abbreviations defined in glossary. †NNTs provided by author. | ||||
| Incidence of metabolic syndrome | ILS v placebo | 38% v 61% | 41% (28 to 52) | 4 (3 to 7) |
| Metformin v placebo | 50% v 61% | 17% (0 to 31) | 9 (5 to 41) | |