Metoclopramide for acute migraine*
| Outcomes at 1 week | Number of trials (n) | Comparison | Weighted event rates | RBI (95% CI) | NNT (CI) |
|---|---|---|---|---|---|
| *Abbreviations defined in glossary; weighted event rates, RBI, NNT, and CI calculated from data in article using a random effects model. †Not significant. | |||||
| Reduction in headache pain | 3 (185) | Metoclopramide v placebo | 56% vs 31% | 80% (1 to 221) | 4 (3 to 44) |
| Odds ratio (CI) | |||||
| 2 (161) | Metoclopramide v other AEs | 0.39 (0.18 to 0.87) | |||
| Complete relief of headache | 1 (62) | Combination metoclopramide v other AMs | 7.79 (1.79 to 33.86) | ||