≥1 vertebral fracture with raloxifene v placebo in postmenopausal osteoporosis at 3 years†

WomenRaloxifene doseRaloxifenePlaceboRRR (95%)NNT
†Abbreviations defined in glossary; RRR, NNT, and CI calculated from data in article.
All 60 mg/d6.6%10.1%35% (21 to 47)29 (20 to 52)
120 mg/d5.4%10.1%46% (33 to 56)22 (17 to 33)
With previous fractures 60 mg/d14.7%21.2%35% (19 to 48)16 (10 to 38)
120 mg/d10.7%21.2%53% (40 to 63)10 (7 to 15)
With no previous fractures 60 mg/d2.3% 4.5%47% (22 to 65)47 (29 to 120)
120 mg/d2.8% 4.5%38% (9 to 57)59 (33 to 274)