Aspirin v warfarin for symptomatic intracranial arterial stenosis at mean 1.8 years*

OutcomesAspirinWarfarinRRI (CI)NNH
Primary composite endpoint†22.1%21.8%4% (−25 to 40)Not significant
RRR (CI)NNT (CI)
*MI  =  myocardial infarction. Other abbreviations defined in glossary; NNT and CI calculated from data in article.
†Primary composite outcome  =  ischaemic stroke, brain haemorrhage, and death from vascular causes other than stroke.
All cause death4.3%9.7%53% (10 to 76)20 (14 to 108)
Vascular death3.2%5.9%43% (−25 to 74)Not significant
Non-vascular death1.1%3.8%70% (−7 to 92)Not significant
Major haemorrhage3.2%8.3%60% (15 to 81)18 (13 to 67)
MI or sudden death2.9%7.3%59% (9 to 81)24 (17 to 158)