Table 2

. Metoprolol (Met) v placebo for acute myocardial infarction at up to 28 days*

OutcomesMetPlaceboRRR (95% CI)NNT (CI)
Composite end point†9.4%9.9%3.6% (−0.9 to 9.1)Not significant
Death7.7%7.8%0.9% (−4.6 to 7.4)Not significant
Reinfarction2.0%2.5%18% (7.8 to 28)229 (147 to 517)
Ventricular fibrillation2.5%3.0%17% (6.8 to 24)199 (135 to 483)
RRI (CI)NNH (CI)
*Abbreviations defined in glossary; RRR, RRI, NNT, NNH, and CI calculated from data in article.
†Death, reinfarction, or cardiac arrest.
Other cardiac arrest3.0%2.8%7.8% (−2.9 to 20)Not significant
Cardiogenic shock5.0%3.9%29% (18 to 39)91 (67 to 143)
Composite end point† or shock10.9%10.8%1.8% (−3.6 to 7.1)Not significant