Endoscopic gastroduodenal ulcers ≥3 mm with rofecoxib and placebo v ibuprofen for osteoarthritis†
| Comparison at 12 wk | Event rates | RRR (95% CI) | NNT (CI) |
|---|---|---|---|
| †Abbreviations defined in glossary; RRR, NNT, and CI calculated using simple proportions with data provided by author. | |||
| Rofecoxib, 25 mg/d, v ibuprofen | 4% v 25% | 85% (68 to 93) | 5 (3 to 7) |
| Rofecoxib, 50 mg/d, v ibuprofen | 7% v 25% | 73% 52 to 85) | 5 (4 to 9) |
| Placebo v ibuprofen | 7% v 25% | 72% (49 to 85) | 5 (4 to 10) |