Calcium antagonists (CAs) v other antihypertensive agents in hypertension*
| Weighted event rates | ||||
|---|---|---|---|---|
| Outcomes | CAs | Other agents | RRI (95% CI) | NNH (CI) |
| MI | 4.5% | 3.6% | 25% (11 to 41) | 110 (67 to 259) |
| Congestive heart failure | 3.3% | 2.7% | 24% (7 to 44) | 152 (83 to 538) |
| Major cardiovascular events | 14.2% | 13.1% | 24% (7 to 44) | 90 (51 to 442) |
| All-cause mortality | 8.3% | 8.1% | 3% (−6 to 12) | Not significant |
| CAs | Other agents | RRR (CI) | NNT (CI) | |
|---|---|---|---|---|
| * Follow up ranged from 2–7 years. MI = myocardial infarction. Other abbreviations defined in glossary; RRI, RRR, NNH, NNT, and CI calculated from data in article. | ||||
| Stroke | 4.5% | 5.0% | 10% (−2 to 19) | Not significant |