Antihypertensive drug comparisons in patients with hypertension, diabetes mellitus, coronary artery disease, or renal disease*
| Outcomes | Comparison | Event rates | RRR (95% CI) | NNT (CI) |
|---|---|---|---|---|
| Stroke | CA v D or β | 3.9% v 4.3% | 13% (2 to 23) | 172 (97 to 1113) |
| RRI | NNH (CI) | |||
|---|---|---|---|---|
| *Follow up ranged from 4–5 years. β = β-blocker; CA = calcium antagonist; D = diuretic; CAD = coronary artery disease. Other abbreviations defined in glossary; RRR, RRI, NNT, NNH, and CI calculated from data in article. | ||||
| CAD | CA v D or β | 4.9% v 4.3% | 12% (0 to 26) | Borderline significance |