Amoxicillin v placebo for children ≤2 years of age with acute otitis media‡
| Outcomes | Amoxicillin | Placebo | RRR (95% CI) | NNT (CI) |
|---|---|---|---|---|
| Persistent symptoms at 4 days | 59% | 72% | 18% (2 to 33) | 8 (4 to 72) |
| Adjusted RRR (CI) | Adjusted NNT (CI) | |||
|---|---|---|---|---|
| 14% (0.8 to 24) | 10 (6 to 169) |
| RRR (CI) | NNT | |||
|---|---|---|---|---|
| ‡Adjustment was made for unequal baseline distribution of recurrence, day care attendance, and smoking. Abbreviations defined in glossary; RRR, NNT, and CI calculated from data in article. | ||||
| Clinical failure at 11 days | 64% | 70% | 8% (−10 to 24) | Not significant |