d -dimer assay and clinical assessment to diagnose deep venous thrombosis (DVT) in symptomatic limbs†
| Test strategy | DVT | Sensitivity | Specificity | +LR | −LR |
|---|---|---|---|---|---|
| †LRs defined in glossary and calculated from data in article. | |||||
| d-dimer alone | All | 87% | 57% | 2.0 | 0.3 |
| Proximal | 89% | 55% | 2.0 | 0.02 | |
| Calf | 81% | 50% | 2.0 | 0.4 | |
| d-dimer plus clinical assessment | All | 96% | 46% | 1.8 | 0.09 |
| Proximal | 98% | 43% | 1.7 | 0.05 | |
| Calf | 91% | 38% | 1.5 | 0.2 | |