Percentage of change in FEV1 for cardioselective β-blockers v placebo in chronic obstructive pulmonary disease†

Type of treatmentNumber of trialsFollow-upWMD (95% CI)
†WMD = weighted mean difference; other abbreviations defined in glossary. All analyses used a fixed-effects model.
Single dose2 (n = 50){1 to 6 h}*−2.05 (−6.05 to 1.96)
Longer duration4 (n = 140)1 to 8 wk−2.55 (−5.94 to 0.84)