Antioxidant vitamins v placebo for high risk patients at mean 5 year follow up†
| Outcomes | Antioxidant vitamins | Placebo | RRI (95% CI) | NNH |
|---|---|---|---|---|
| All cause mortality | 14.1% | 13.5% | 4% (−3 to 12) | Not significant |
| Vascular mortality | 8.6% | 8.2% | 5% (−5 to 15) | Not significant |
| Nonvascular mortality | 5.5% | 5.3% | 4% (−8 to 17) | Not significant |
| Major coronary event‡ | 10.4% | 10.2% | 2% (−6 to 11) | Not significant |
| RRR (CI) | NNT | |||
|---|---|---|---|---|
| †Antioxidant vitamins were vitamin E, vitamin C, and β carotene. Abbreviations defined in glossary; RRI, RRR, NNT, NNH, and CI calculated from data in article. | ||||
| ‡Nonfatal myocardial infarction or death from coronary disease. | ||||
| Stroke | 5.0% | 5.0% | 1% (−12 to 13) | Not significant |
| Revascularisation | 10.3% | 10.6% | 2% (−6 to 10) | Not significant |
| Cancer (except nonmelanoma skin cancer) | 7.8% | 8.0% | 2% (−8 to 11) | Not significant |