Mefloquine (Mef) v placebo (Pl) or other prophylaxis (Other) in adult travellers not immune to malarial infection†
| Outcomes | Comparison | Event rates | RRR (95% CI) | NNT (CI) |
|---|---|---|---|---|
| Malaria (1 study) | Mef v Pl | 0% v 77% | 100% (93 to 100) | 2 (2 to 2) |
| Weighted event rates | RRI (CI) | NNH (CI) | ||
| †A fixed effects model was used. Abbreviations defined in glossary; RRR, RRI, NNT, NNH, and CI calculated from data in article. | ||||
| Withdrawal | Mef v Pl | 4.3% v 1.2% | 238% (62 to 603) | 33 (21 to 72) |
| Fatigue | Mef v Other | 7.9% v 5.3% | 50% (0 to 125) | 39 (20 to 1000) |
| Insomnia | Mef v Other | 14.7% v 9.5% | 55% (15 to 108) | 20 (12 to 56) |