Antiplatelet treatment added to oral anticoagulants (combined therapy) v anticoagulants alone (single treatment) for patients with mechanical prosthetic heart valves (follow up 1 to 2.5 y)*
| Weighted event rates | ||||
|---|---|---|---|---|
| Outcomes | Combined treatment | Single treatment | RRR (95% CI) | NNT (CI) |
| *Abbreviations defined in glossary. Weighted event rates, RRI, and NNH and related CIs calculated from data in article. | ||||
| Thromboembolic events | 5.5% | 8.9% | 57% (38 to 70) | 30 (19 to 62) |
| All cause mortality | 5.8% | 9.5% | 49% (35 to 67) | 27 (18 to 35) |
| RRI (CI) | NNH (CI) | |||
| Haemorrhagic events | 6.4% | 5.0% | 45% (3 to 106) | 72 (31 to 222) |