Oestradiol-17β v placebo for postmenopausal women with ischaemic stroke or transient ischaemic attack‡

Outcomes at mean 2.8 yearsOestradiol-17βPlaceboRRI (95% CI)NNH
‡Abbreviations defined in glossary; RRI, RRR, NNH, NNT, and CI calculated from Cox proportional hazards data in article.
Death or non-fatal stroke29%28% 8.3% (–17 to 32)Not significant
Fatal stroke 3.6% 1.2%187% (–9.9 to 758)Not significant
Transient ischaemic attack 8.9% 7.6% 19% (–29 to 92)Not significant
Non-fatal myocardial infarction 4.2% 3.7% 20% (–50 to 143)Not significant
RRR (CI) NNT
Venous thromboembolic event 0.89% 1.2%20% (–235 to 80)Not significant
Breast cancer 1.5% 1.5% 0% (–243 to 70)Not significant