Element | Example 1 | Example 2 | |||
---|---|---|---|---|---|
Short title | Palpation for abdominal aortic aneurysm (AAA) | Ferritin for iron deficiency | |||
Bottom line | 1. Abnormal aortic contour on palpation can raise probability of AAA greatly.2. Normal palpation cannot accurately rule out AAA. | 1. In suspected iron deficiency, serum ferritin is accurate and precise, dominating other tests, even with inflammatory disease. | |||
2. Normal palpation cannot accurately rule out AAA. |
Results | Size of aneurysm | +LR | −LR | Ferritin measurement (ng/ml) | LR |
---|---|---|---|---|---|
>3 cm | 12.0 | 0.72 | <15 | 51.85 | |
>4 cm | 15.6 | 0.51 | >15 to <25 | 8.83 | |
>25 to <35 | 2.54 | ||||
>35 to <45 | 1.83 | ||||
>45 to <100 | 0.54 | ||||
>100 | 0.08 | ||||
Source | Systematic review of studies of examination for AAA, involving 2955 patients | Systematic review of studies with marrow iron as standard, involving 2579 patients | |||
Citation | JAMA 1999;281:77–82. | J Gen Intern Med 1992;7:145–53. | |||
eCAT date | 9 January 1999 | 10 August 1998 |