Events/1000 person years | |||||
---|---|---|---|---|---|
Risk factor interventions | Number of studies | Treatment | Control | Summary rate ratio (95% CI) | Person-years needed to treat (CI) |
*Death from coronary heart disease and non-fatal myocardial infarction. †Summary rate ratios were calculated using a fixed effects model. NM = not clinically meaningful because person years needed to treat is negative. | |||||
Cholesterol lowering | 5 | 30 | 41 | 0.75 (0.61 to 0.93) | 106 (62 to 366) |
Primary prevention | 2 | 8 | 19 | 0.44 (0.17 to 1.2) | 97 (45 to NM) |
Secondary prevention | 3 | 34 | 44 | 0.77 (0.62 to 0.96) | 120 (61 to 48 056) |
Blood pressure lowering | 3 | 17 | 23 | 0.73 (0.57 to 0.94) | 157 (88 to 726) |
Glucose lowering | 2 | 15 | 18 | 0.87 (0.74 to 1.01) | Not significant |