Oestrogen plus progestin (O + P) v placebo in postmenopausal women at mean 5.6 years*
| Outcomes | O + P v placebo | RRR (95% CI) | NNT (CI) |
|---|---|---|---|
| *Abbreviations defined in glossary; RRR, NNT, and CI calculated from data in article using Cox proportional hazards model. | |||
| Any fracture | 8.6% v 11% | 23% (16 to 30) | 40 (31 to 56) |
| Hip fracture | 0.6% v 0.9% | 33% (4.0 to 53) | 338 (210 to 2787) |
| Hazard ratio (CI) | |||
| Lower arm or wrist fracture | 0.71 (0.59 to 0.85) | ||
| Vertebral fracture | 0.65 (0.46 to 0.92) | ||