Continuation of antidepressant therapy v placebo for depressive disorder*
| Weighted event rates | ||||
|---|---|---|---|---|
| Outcomes | Antidepressants | Placebo | RRR (95% CI) | NNT (CI) |
| *Abbreviations defined in glossary; weighted event rates, RRR, NNT, and CI calculated from data in article. | ||||
| Overall rate of relapse at 6–36 months (32 studies) | 11% | 41% | 57% (48 to 64) | 4 (3 to 6) |
| First recurrences at various time intervals after randomisation (6 studies): | ||||
| 0–12 months | 18% | 60% | 65% (52 to 75) | 3 (2 to 4) |
| 12–36 months | 15% | 29% | 66% (35 to 82) | 8 (4 to 33) |
| 0–36 months | 22% | 51% | 65% (54 to 74) | 4 (3 to 7) |