Outcomes | Number of RCTs | Weighted mean difference (95% CI) | |||
---|---|---|---|---|---|
Systolic BP (mm Hg) at 6–12 months | 7 | −2.5 (−3.8 to −1.2) | |||
Diastolic BP (mm Hg) at 6–12 months | 7 | −1.2 (−1.8 to −0.7) | |||
Systolic BP (mm Hg) at 13–60 months | 4 | −1.1 (−1.8 to −0.4) | |||
Diastolic BP (mm Hg) at 13–60 months | 4 | −0.6 (−1.5 to 0.3)† |
Weighted event rates | RRR (95% CI) | NNT | |||
---|---|---|---|---|---|
Total mortality | 3 | 0.69% | 0.73% | 10% (−124 to 36) | Not significant |
Cardiovascular morbidity | 2 | 11% | 14% | 18% (−21 to 41) | Not significant |
RRI (CI) | NNH | ||||
---|---|---|---|---|---|
*BP = blood pressure; RCTs = randomised controlled trials. Other abbreviations defined in glossary; weighted event rates, RRR, RRI, NNT, NNH, and CI calculated from data in article. | |||||
†Not significant. | |||||
Dropouts | 9 | 12% | 11% | 4% (−14 to 25) | Not significant |