Naltrexone for 3 months (short term) or 12 months (long term) v placebo for alcohol dependence‡
| Outcomes at 13 weeks | Comparison | Means | Difference between groups (95% CI) |
|---|---|---|---|
| Number of days to relapse | Short or long term v placebo | 72.3 v 62.4 | 9.9 (–3.0 to 22.8) |
| Outcomes at 52 weeks | |||
|---|---|---|---|
| ‡CI defined in glossary. None of the mean differences are statistically significant. | |||
| §NDPDD evaluated for the 66% of patients who consumed alcohol during follow up. | |||
| Percentage of drinking days | Long term v placebo | 15.1 v 18.0 | –2.9 (–7.7 to 1.9) |
| Short term v placebo | 19.4 v 18.0 | 1.4 (–3.6 to 6.5) | |
| Number of drinks per drinking day (NDPDD)§ | Long term v placebo | 9.6 v 9.3 | 0.3 (–1.8 to 2.4) |
| Short term v placebo | 10.5 v 9.3 | 1.2 (–0.5 to 2.9) | |