Characteristics of d -dimer test for suspected venous thromboembolism (VTE) (deep venous thrombosis [DVT] or pulmonary embolism [PE]) for varying pre-test probabilities (PPs)*
| Disease | PP | Patients | Sensitivity (95% CI) | Specificity (CI) | +LR | −LR |
|---|---|---|---|---|---|---|
| *Diagnostic terms defined in glossary; +LRs calculated from data in article. | ||||||
| VTE | All | All | 96% (90 to 99) | 45% (40 to 49) | 1.8 | 0.09 |
| Low | All | 100% (74 to 100) | 54% (47 to 61) | 2.2 | 0.0 | |
| Intermediate | All | 96% (86 to 100) | 40% (36 to 46) | 1.6 | 0.10 | |
| High | All | 93% (82 to 99) | 28% (14 to 44) | 1.3 | 0.25 | |
| All | Cancer | 97% (82 to 100) | 46% (30 to 63) | 1.8 | 0.07 | |
| DVT | All | All | 97% (89 to 100) | 47% (40 to 53) | 1.8 | 0.06 |
| PE | All | All | 94% (83 to 99) | 42% (36 to 40) | 1.6 | 0.14 |