Response to prednisolone v placebo according to smoking status in patients with stable chronic asthma*
| Mean difference (95% confidence interval) | |||
|---|---|---|---|
| Outcomes† | Current smokers (n = 14) | Ex-smokers (n = 10) | Never-smokers (n = 26) |
| * FEV1 = forced expiratory volume in 1 second, PEF = peak expiratory flow. | |||
| †Change after corticosteroids compared with placebo. | |||
| ‡6 point scale, 0 = well controlled and 6 = poorly controlled. | |||
| Change in FEV1 prealbuterol (ml) | 47 (−148 to 243) | 143 (−223 to 510) | 237 (43 to 431) |
| Change in morning PEF (l/m) | 6.5 (−13 to 26) | 29.1 (2.3 to 56) | 36.8 (11.4 to 62) |
| Asthma control score‡ | −0.05 (−0.7 to 0.6) | –0.61 (−1 to 0.2) | −0.72 (−1 to −0.3) |