Diagnostic characteristics of 3 screening questionnaires and unaided clinical diagnosis for detecting depression†

TestsSensitivity (95% CI)Specificity (CI)PPVNPV+LR−LR
†WHO-5 = World Health Organization Wellbeing Index; GHQ-12 = General Health Questionnaire; PHQ-9 = Brief Patient Health Questionnaire, 9 items; PPV = positive predictive value; NPV = negative predictive value. Diagnostic terms defined in glossary; LRs calculated from data in article.
WHO-593% (95 to 98)64% (59 to 69)34%98%2.580.11
CHQ-1285% (74 to 92)62% (57 to 67)31%95%2.240.24
PHQ-978% (66 to 87)85% (81 to 89)51%95%5.200.26
Clinical diagnosis65% (53 to 76)74% (69 to 79)34%91%2.500.47