Cannabis v active antiemetic or placebo at 24 hours in patients with chemotherapy-induced sickness*
| Outcome (number of studies) | Other drug | Weighted event rates | RBI (95% CI) | NNT (CI) |
|---|---|---|---|---|
| Complete nausea relief (7) | Active | 59% v 43% | 38% (18 to 62) | 7 (4 to 16) |
| Complete vomiting relief (6) | Active | 57% v 45% | 28% (8 to 51) | 8 (5 to 38) |
| “High” sensation (8) | Active or placebo | 35% v 3% | 10% (6 to 16) | 4 (3 to 4) |
| Drowsiness or sedation (15) | Active or placebo | 50% v 30% | 66% (46 to 89) | 5 (4 to 7) |
| Euphoria (3) | Active | 14% v 1% | 12% (2 to 51) | 8 (6 to 12) |
| RRI (CI) | NNH (CI) | |||
|---|---|---|---|---|
| *Abbreviations defined in glossary; RBI and RRI calculated from data in article using a fixed-effects model; NNT, NNH, and CI provided in article. | ||||
| Dizziness (9) | Active or placebo | 49% v 17% | 3% (1 to 3) | 4 (3 to 4) |
| Dysphoria or depression (10) | Active or placebo | 13% v 0.3% | 7% (2 to 18) | 9 (7 to 12) |
| Hallucination (10) | Active or placebo | 6% v 0% | ∞ | 17 (12 to 27) |
| Paranoia (6) | Active or placebo | 5% v 0% | ∞ | 20 (13 to 42) |
| Hypotension (13) | Active or placebo | 25% v 11% | 1% (1 to 2) | 8 (6 to 11) |