Clozapine v chlorpromazine in schizophrenia at 4–12 weeks*

Weighted event rates
OutcomesNumber of RCTs (n)ClozapineChlorpromazineRRR (95% CI)NNT (CI)
*EPS = extrapyramidal side effect; RCTs = randomised controlled trials. Abbreviations defined in glossary; RRR, NNT, and CI calculated from data in article.
Number of patients with ≥1 EPS11 (755)11%26%44% (15 to 62)7 (4 to 25)