Cost-effectiveness of colorectal cancer screening as reported in selected articles*
| “Bottom Line” (cost per life-year gained, 1998 dollars) (reference)† | |||
|---|---|---|---|
| Interventions compared | Sonnenberg (4) | Frazier (5) | Vijan(6) |
| *FOBT = fecal occult blood test; FS = flexible sigmoidoscopy. | |||
| †Baseline compliance: Sonnenberg 100%, Frazier 60%, Vijan 75%. | |||
| ‡Dominates means that the second procedure listed was more costly and less effective than the first procedure. | |||
| §FOBT plus flexible sigmoidoscopy is more expensive and more effective than colonoscopy. | |||
| Annual FOBT v no screening | $9705 | $12 667 | $7756 |
| FS every 5 years v no screening | $36 509 | $12 571 | $14 668 |
| Colonoscopy v no screening | $10 983 | $20 418 | $7019 |
| Colonoscopy v annual FOBT | $11 382 | $76 552 | $6243 |
| Colonoscopy v FS every 5 years | Dominates‡ | $52 903 | Dominates‡ |
| Colonoscopy v FS every 5 years plus annual FOBT | Not available | $561§ | $332 630§ |