25. Clinical applicability of findings | 14 | 98 | 41–100 | 5 | 98 | 84–99 |
4. Participant recruitment | 16 | 85 | 55–100 | 7 | 93 | 60–98 |
2. Research questions/aims | 14 | 84 | 24–100 | 5 | 88 | 76–96 |
8. Technique of | 16 | 73 | 31–98 | 7 | 74 | 40–97 |
a. Index test | 5 | 92 | 49–95 | 4 | 84 | 58–97 |
b. Reference standard | 5 | 63 | 13–86 | 4 | 55 | 23–72 |
15. Characteristics of study population | 16 | 73 | 42–90 | 7 | 70 | 60–93 |
7. Reference standard and rationale | 16 | 70 | 28–98 | 7 | 76 | 45–98 |
9. Units/cut-offs/categories for | 16 | 70 | 0–98 | 7 | 83 | 63–85 |
a. Index test | 5 | 84 | 68–95 | 4 | 91 | 71–94 |
b. Reference standard | 5 | 73 | 55–76 | 4 | 75 | 56–80 |
3. Study population | 16 | 68 | 23–92 | 7 | 63 | 21–88 |
6. Data collection | 16 | 68 | 21–100 | 7 | 83 | 43–95 |
19. Cross tabulation of results | 15 | 65 | 2–99 | 6 | 66 | 28–99 |
18. Distribution of severity of disease | 16 | 62 | 0–97 | 7 | 52 | 11–98 |
21. Estimates of diagnostic accuracy | 15 | 56 | 12–97 | 6 | 56 | 22–97 |
12. Methods for statistics used | 15 | 49 | 8–90 | 6 | 49 | 11–90 |
14. Dates of study | 16 | 47 | 6–73 | 7 | 73 | 42–81 |
1. Study identified as test accuracy study | 13 | 40 | 8–100 | 5 | 24 | 18–99 |
5. Participant sampling | 16 | 40 | 12–89 | 7 | 64 | 31–89 |
23. Estimates of variability of accuracy | 15 | 37 | 0–100 | 6 | 39 | 0–100 |
17. Time interval between tests | 15 | 34 | 0–77 | 6 | 38 | 25–74 |
11. Blinding of results of | 16 | 29 | 14–54 | 7 | 33 | 16–55 |
a. Index test | 5 | 43 | 33–72 | 4 | 50 | 26–67 |
b. Reference test | 5 | 23 | 12–48 | 4 | 25 | 15–48 |
22. How uninterpretable results were handled | 15 | 28 | 8–62 | 6 | 25 | 8–57 |
10. Persons executing | 16 | 26 | 2–73 | 7 | 20 | 2–42 |
a. Index test | 5 | 33 | 7–46 | 4 | 26 | 4–51 |
b. Reference standard | 5 | 20 | 0–35 | 4 | 14 | 0–33 |
16. Eligible patients not undergoing either test | 16 | 24 | 5–78 | 7 | 53 | 13–70 |
a. Flow diagram | 12 | 5 | 0–16 | 4 | 8 | 0–22 |
13. Methods for test reproducibility for: | 15 | 16 | 0–88 | 6 | 18 | 0–88 |
a. Index test | 4 | 20 | 12–53 | 3 | 35 | 6–48 |
b. Reference standard | 4 | 7 | 0–12 | 3 | 4 | 0–6 |
24. Estimates of test reproducibility, for: | 15 | 8 | 0–96 | 6 | 8 | 0–96 |
a. Index test | 4 | 20 | 13–38 | 3 | 22 | 6–44 |
b. Reference standard | 4 | 3 | 0–8 | 3 | 0 | 0–6 |
20. Adverse events | 12 | 7 | 0–33 | 6 | 11 | 1–18 |