Overall bottom-line recommendations by organ system/specialty classification, sorted by the percentage of recommendations that are A or B
| Category | Topics in category (n) | A | B | C | A or B* | B or C† | Total |
| Pregnancy and childbirth | 16 | 26 (36%) | 23 (32%) | 23 (32%) | 49 (68%) | 46 (64%) | 72 |
| Cardiovascular | 49 | 66 (30%) | 85 (38%) | 71 (32%) | 151 (68%) | 156 (70%) | 222 |
| Oncology | 39 | 35 (20%) | 78 (44%) | 65 (37%) | 113 (63%) | 143 (80%) | 178 |
| Psychiatric | 20 | 27 (28%) | 33 (35%) | 35 (37%) | 60 (63%) | 68 (72%) | 95 |
| Neurological | 48 | 40 (19%) | 85 (41%) | 84 (40%) | 125 (60%) | 169 (81%) | 209 |
| Gastrointestinal | 58 | 59 (20%) | 112 (39%) | 119 (41%) | 171 (59%) | 231 (80%) | 290 |
| Respiratory | 36 | 36 (23%) | 53 (34%) | 69 (44%) | 89 (56%) | 122 (77%) | 158 |
| Congenital | 23 | 16 (16%) | 36 (37%) | 46 (47%) | 52 (53%) | 82 (84%) | 98 |
| Gynaecological | 29 | 27 (20%) | 44 (32%) | 66 (48%) | 71 (52%) | 110 (80%) | 137 |
| Skin disease | 56 | 46 (19%) | 82 (33%) | 120 (48%) | 128 (52%) | 202 (81%) | 248 |
| Musculoskeletal and rheumatological | 61 | 31 (11%) | 102 (37%) | 140 (51%) | 133 (49%) | 242 (89%) | 273 |
| Renal | 20 | 13 (14%) | 31 (33%) | 49 (53%) | 44 (47%) | 80 (86%) | 93 |
| Male genitourinary | 18 | 11 (15%) | 24 (32%) | 40 (53%) | 35 (47%) | 64 (85%) | 75 |
| Infectious disease | 61 | 41 (15%) | 77 (29%) | 147 (55%) | 118 (45%) | 224 (85%) | 265 |
| Trauma and injuries | 32 | 21 (15%) | 39 (28%) | 77 (56%) | 60 (44%) | 116 (85%) | 137 |
| Perinatal and infant | 17 | 10 (12%) | 26 (31%) | 47 (57%) | 36 (43%) | 74 (88%) | 83 |
| Haematological | 20 | 7 (8%) | 31 (35%) | 50 (57%) | 38 (43%) | 81 (92%) | 88 |
| Eye diseases | 23 | 19 (18%) | 25 (24%) | 61 (58%) | 44 (42%) | 86 (82%) | 105 |
| Ear, nose and throat/allergy | 36 | 17 (12%) | 38 (28%) | 83 (60%) | 55 (40%) | 121 (88%) | 138 |
| Endocrine | 41 | 25 (13%) | 47 (25%) | 114 (61%) | 72 (39%) | 161 (87%) | 186 |
| Poisoning and toxicity | 18 | 3 (4%) | 24 (29%) | 56 (67%) | 27 (33%) | 80 (96%) | 83 |
*Recommendations based on patient-oriented evidence (improvements in how well or long patients live).
†Studies with inconsistent evidence of benefit, low-validity studies, or based on disease-oriented evidence.