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BMJ Journals

Drugs: cardiovascular system

Percutaneous coronary intervention for acute coronary syndromes: no difference in 30-day efficacy or safety of high- and low-dose aspirin; double-dose clopidogrel reduces 30-day risk of cardiovascular death, myocardial infarction or stroke compared with standard dose but increases risk of major bleeding
Anuradha Lala, Jeffrey S Berger

BMJ Evidence-Based Medicine Jun 2011, 16 (3) 80-81; DOI: 10.1136/ebm1187
Symptomatic carotid stenosis: relative to endarterectomy, stenting increases short-term risk of stroke or death in those aged over 70 years but not in younger patients
Martin Wiesmann

BMJ Evidence-Based Medicine Jun 2011, 16 (3) 85-86; DOI: 10.1136/ebm1192
Carvedilol reduced mortality and hospital admission in severe chronic heart failure, regardless of pretreatment systolic BP
BMJ Evidence-Based Medicine Feb 2005, 10 (1) 9; DOI: 10.1136/ebm.10.1.9
Blood pressure lowering in patients with type 2 diabetes improves cardiovascular events including mortality, but more intensive lowering to systolic blood pressure less than 130 mm Hg is associated with further reduction in stroke and albuminuria without further reduction in cardiac events
Bora Toklu, Sripal Bangalore

BMJ Evidence-Based Medicine Oct 2015, 20 (5) 183-184; DOI: 10.1136/ebmed-2015-110197
Lowering diastolic blood pressure in non-proteinuric hypertension in pregnancy is not harmful to the fetus and is associated with reduced frequency of severe maternal hypertension
Phyllis August

BMJ Evidence-Based Medicine Aug 2015, 20 (4) 141; DOI: 10.1136/ebmed-2015-110203
The mortality rate in England between 2007 and 2012 was not associated with the quality of primary care in an established pay for performance programme
Robert Fleetcroft

BMJ Evidence-Based Medicine Aug 2015, 20 (4) 149; DOI: 10.1136/ebmed-2015-110205
Potential cost-savings may be considerable with management of hypertension according to updated US hypertension guidelines, but for women aged 35–44 years these benefits are unlikely
Dominique A Cadilhac, Joosup Kim

BMJ Evidence-Based Medicine Aug 2015, 20 (4) 150; DOI: 10.1136/ebmed-2015-110202
Evidence suggests dabigatran is an effective and safe treatment for patients with VTE requiring early parenteral therapy
Serena Granziera, Alexander T Cohen

BMJ Evidence-Based Medicine Oct 2014, 19 (5) 180; DOI: 10.1136/ebmed-2014-110008
Non-vitamin-K oral anticoagulants reduce mortality, stroke and intracranial haemorrhage when compared with warfarin in randomised trials of patients with non-valvular atrial fibrillation
Benjamin A Steinberg

BMJ Evidence-Based Medicine Oct 2014, 19 (5) 182; DOI: 10.1136/ebmed-2014-110004
Risk of venous thrombosis varies with different types of combined oral contraceptives
Maria T DeSancho

BMJ Evidence-Based Medicine Apr 2014, 19 (2) e11; DOI: 10.1136/eb-2013-101605

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